Coach between Hong Kong and Guangzhou
Diversity coach routes are available between HongKong and cities in pearl river delta including Guangzhou . There are shuttle buses between HK airport and Guangzhou downtown, also between HK downtown and Guangzhou downtown.

From Hong Kong
Travel to Guangzhou ( Canton ) through the Hong Kong International Airport is easy and convenient. Airport-Guangzhou coach services are available in the Arrivals Hall. Regular services depart from the airport between 7:00 a.m. and 11:00 p.m. Passengers are reminded that presentation of valid travel document for the entry of Mainland of China is required before boarding the coaches.

From Guangzhou
There are also lots of non-stop bus from Guangzhou ( Canton ) to Hong Kong . You can take a direct bus from Guangzhou to Hong Kong from some hotels in Guangzhou such as: the China Hotel, Garden Hotel, Guangzhou Hotel and Hotel Landmark Canton.

Bus departs from 05:30 to 20:00, every half an hour
Price: 100 yuan (single ticket), 160 yuan (round-trip ticket)
Time: 3-4 hours

Train between Hong Kong and Guangzhou
Many travelers arrive from HongKong to mainland China will take train from HongKong to Guangzhou directly. The Kowloon-Canton (guangzhou) Railway runs between Hung Hom in Kowloon and then Shenzhen city , Dongguan city of Guangdong Province and reach at Guangzhou East Railway Station, linking mainland China to Hong Kong. The whole journey will take about 2 hours.Traveling by train is a good alternative for casual budget-conscious travelers as the train ticket price is one-third that of an air ticket.

Hung Hom train station (HK)
The Hung Hom train station, also called Hung Hom KCR station, is the terminus for rail travel into Mainland China, it located in Kowloon area of HongKong, has a variety of stores. The Metropolis Mall is a shopping centre located beside the Hung Hom KCR Station.
  
Guangzhou east railway station
The Guangzhou east railway station located in Guangzhou downtown area, in the heart of Tianhe district. Convenient to most places and hotels in Guangzhou downtown. It is the mainly for the HK(kowloon) to Guangzhou train terminal, meanwhile for some domestic train between Guangzhou and other cities in mainland China.

Guangzhou railway station
This is one of the biggest train station in China, but it is mainly for domestic trains between Guangzhou and other cities in mainland China. Generally, most foreigners using air planes for traveling between cities inside china mainland, strangers may feel confused at China's domestic train stations without guide.

Shenzhen railway station
Shenzhen railway station located in Shenzhen downtown area, Luohu district. There are trains from here directly to HongKong and also trains directly to Guangzhou city(Guangzhou east railway station), as well as trains between Shenzhen and other cities in China. 

Ferry from Hong Kong to Guangzhou
Ferry is available from Hong Kong to Guangzhou , there are two main ferry ports in HongKong, one is the Hong Kong China Ferry Terminal and the other is the HK intl airport ferry port. From both ports, there are ferry available to Lian Hua Mountain Port in Panyu district, Guangzhou.

Lianhuashan Ferry Terminal
The Lianhuashan Ferry Terminal located in Shilou Town, Panyu District, Guangzhou . Panyu is one of the suburb districts of Guangzhou , and the Ferry terminal is about 25KM from downtown area.

Nansha port
The Nansha port also located in the Panyu district in Guangzhou . It will take about 80 mins from Nansha port to HongKong China Hong Kong City Terminal

Tsim Sha Tsui MTR station
China Hong Kong City is one of Hong Kong 's most prominent commercial complexes. Conveniently located on Canton Road, Tsim Sha Tsui - Kowloon 's busiest business and tourist district - this massive development includes five broadband-enabled office towers with spectacular seaviews, a comprehensive shopping mall, the Royal Pacific Hotel & Towers, China Ferry Terminal, bus and taxi terminals. It is also well served by all major means of public transport and is only a few minutes' walk from Tsim Sha Tsui MTR station.